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Researchers

Grants and Funding

TSC Biosample Seed Grants Available

The TSC Alliance announces a funding opportunity for 2022 Biosample Seed Grants to support research using blood, tissue, and/or cells, DNA, or RNA isolated from samples in the TSC Biosample Repository. The award may support laboratory supplies, personnel costs, services, or equipment necessary to conduct the proposed research. Funds requested can be up to $20,000. Funding period is one year.

The TSC Biosample Repository houses human biological materials linked to detailed clinical data in the TSC Natural History Database. High-quality biosamples and their associated clinical data enable researchers to discover biomarkers, establish human cell lines or tissue arrays for drug testing, and search for clues to understand why TSC is so different from person to person.

Requirements/Eligibility

  • To build the dataset associated with each biosample and avoid duplication of work in the future, applicants will be required to share data generated on each sample back to the TSC Biosample Repository.
    • Data can be embargoed for a period of time to be defined in the Material Transfer Agreement to provide time to publish, protect intellectual property, etc.
  • This opportunity is open to all investigators at established academic or research institutions worldwide.
    • Researchers at start-up pharmaceutical or biotech companies are eligible if they are unable to utilize TSC biosamples in absence of seed funding.
  • Researchers residing in the United States need not be U.S. citizens to apply.
  • We welcome applications from tenure-track faculty or equivalent, non-tenure-track faculty, and postdoctoral (PhD or MD) fellows.

How to Apply

Download the instructions and application below. Compile all application components into a single PDF file and email completed application to Gabrielle Rushing, PhD, at grushing@tscalliance.org AND biosample@tscalliance.org no later than 11 pm Eastern (US/Canada) on Friday, October 28, 2022. Successful applicants will be notified by Monday, November 21, 2022.

Download Application

Please contact Gabrielle Rushing, PhD (grushing@tscalliance.org) with any questions.

2022 Grant Cycle in Progress

The TSC Alliance is dedicated to finding a cure for tuberous sclerosis complex (TSC) while improving the lives of those affected. We invest in early-career researchers to drive innovative TSC research and to foster a diverse group of researchers dedicated to our shared mission. In 2022, we anticipate awarding three or four awards to postdoctoral fellows and early-stage investigators depending on merit, requested budgets, and funds available.

Key Dates

Step in process Due Date
LOI due Monday, April 18
Full proposal invitations distributed Week of June 10
Full proposal due (by invitation only) Monday, August 15
Project start date December 1, 2022

New for 2022: Special Funding Opportunity!

Wong Family Foundation Research Award

Thanks to generous support from the Wong Family Foundation, the TSC Alliance is proud to offer a new funding opportunity as part of our regular research grant and postdoctoral fellowship cycle for 2022. This special two-year award will be designated to the most meritorious application focusing on epilepsy research. All epilepsy-focused Postdoctoral Fellowship and Research Grant candidates will automatically be considered for the Wong Family Foundation Research Award, so no additional information is required during the application process.

  • Areas of emphasis for a project designated the Wong Family Foundation Research Award may include (but are not limited to):
    • Basic research in mechanisms relating to intractability, e.g., multi-drug resistant epilepsy
    • Model development (especially for infantile spasms or intractable epilepsy)
    • New technologies related to epilepsy (imaging, electrophysiology, etc.)

Important changes implemented in recent cycles

  • Efforts to increase diversity, equity, and inclusion of traditionally underrepresented groups in TSC research (for example, see Notice of NIH’s Interest in Diversity, although not all underrepresented populations listed by NIH may be underrepresented in TSC research)
    • The TSC Alliance will work diligently to diversify applications by actively seeking and increasing applications from institutions and researchers underrepresented in TSC research.
    • To measure our progress, applicants will be asked to voluntarily provide information on race, ethnicity, and gender via the Professional Profile in ProposalCentral. This information will be used internally by TSC Alliance and will not be shared with peer reviewers.
  • Emphasis on mentorship and anticipated impact of receiving a Postdoctoral Fellowship on the applicant’s career plans
  •  Limitations on eligibility:
    • Applicants for either a Postdoctoral Fellowship or a Research Grant must fit the NIH definition of an early-stage investigator.
      o Postdoctoral Fellowship applicants must have been a member of the Sponsor’s laboratory for at least 12 months as of the Letter of Intent (LOI) due date.
      o Previous recipients of a TSC Alliance Postdoctoral Fellowship are not eligible to receive a second TSC Alliance Postdoctoral Fellowship award but are eligible to receive a Research Grant as an independent, early-stage investigator.

Types of Grants

Postdoctoral Fellowships

  • Postdoctoral Fellowship awards may support any type of basic or translational research relevant to TSC that provides an outstanding opportunity for the trainee’s professional growth.
  • Postdoctoral Fellowship awards are intended to provide funding for an individual who has recently earned a PhD or MD degree and is working with a Sponsor to perform research relevant to TSC.
  • The Sponsor must be tenure-track faculty or an equivalent level at a research institution or company. The award is intended to fund the applicant’s salary and some of the laboratory supplies or tools necessary to conduct the proposed research. The award is not intended to fund technical support for the project or to purchase equipment in the Sponsor’s laboratory. The trainee applicant is considered to be the “Principal Investigator” for the purpose of postdoctoral fellowship awards.

Research Grants

  • Research Grant proposals should address one of the following four high-priority areas:
    • Understanding phenotypic heterogeneity in TSC, i.e., research on genetic, biologic, or environmental factors that might explain why TSC is so different from person to person
    • Gaining a deeper knowledge of TSC signaling pathways and the cellular consequences of TSC deficiency
    • Improving TSC disease models, whether cell-based, tissue-based, or animal models
    • Developing clinical biomarkers or patient-reported outcome measures for TSC, particularly those that assess disease burden or stratify an individual’s risk of progression or developing specific manifestations of TSC
  • Research Grant awards are intended to provide funding for an independent researcher, whether tenure-track faculty, non-tenure-track faculty or staff, or an equivalent level at a research institution or company. The award may support laboratory supplies, personnel costs, services, or equipment necessary to conduct the proposed research.
  • The TSC Alliance fully supports collaborative projects between co-investigators, but only one investigator may be considered the “Principal Investigator” for the purpose of applying through the online system.

Policies

Duration and Budget

  • Typical duration is two years. Can be shorter if appropriate for the project.
  • Maximum total costs of $75,000 per year ($150,000 total).
    • Postdoctoral Fellowship proposals must include up to $1,500 for travel expenses to attend a relevant scientific meeting. This is optional but strongly encouraged for Research Grant proposals.

Indirect Costs

For research grants, including postdoctoral fellowships, the TSC Alliance allows no more than 10 percent of the total costs to be applied to indirect costs.  As an example, a maximum of $15,000 indirect costs may be included within an award totaling $150,000.

The TSC Alliance does not pay indirect costs on contracts based on delivering a tangible or measurable work product.  Examples of such contracts are those to enter data into the TSC Natural History Database or collection of blood or remnant surgical tissue for the TSC Biosample Repository.

Eligibility

This opportunity is open to all investigators at established academic or research institutions or at pharmaceutical or biotech companies worldwide. Researchers residing in the United States do not need to be U.S. citizens to apply for funding.

Open Science Policy

As a nonprofit funded through contributions from the TSC community and the public at large, we are committed to being good stewards of these funds. We support projects that will rapidly advance our understanding of TSC and the development of therapies for the disease. The TSC Alliance seeks to inspire discovery and innovation by improving access to scientific data and outputs including data, code, software, protocols, and materials. Improved dissemination will lead to more opportunities for TSC investigators to collaborate and for build upon the latest developments in research. In this regard, the TSC Alliance has adopted an Open Science Policy to ensure transparency of and broad access to TSC Alliance-funded research. Please click here to read the policy in its entirety.

Additional Grant Policies

Keith Hall Research Grant Award

The Keith Hall Research Grant Award was established in memory of Keith Hall, an adult with TSC and a former TSC Alliance board chair and community leader. Keith participated extensively in several TSC Alliance volunteer capacities and was a “gentle giant” to so many people who knew him. Keith passed away July 23, 2017 after a battle with cancer and left an incredible legacy of caring for others and inspiring hundreds of children, teens and adults with TSC to embrace life and live it to the fullest, despite any challenges they may face. Keith’s major long-term concerns and goals included:

  • Addressing the needs of adults with TSC
  • Living with kidney involvement
  • Increasing participation to the TSC Natural History Database
  • Donating tissue for research
  • Making involvement in clinical trials easy for anyone
  • Investing in TSC research grants

Each year, the TSC Alliance Board of Directors designates one grant in an area of Keith’s interest as the Keith Hall Research Grant Award.

Current and Previous Grant Awards

Currently Funded Grant Awards

FY 2021

Research Grant Awards

Nicola Alesi, MD, PhD
Brigham and Women’s Hospital
Role of TFEB in the pathogenesis and therapy of TSC kidney manifestations

Gerta Hoxhaj, PhD
UT Southwestern
Defining the genetic factors that mediate purine signals to the TSC network

Philip Iffland, PhD
University of Maryland School of Medicine
Amino acid modulation as a therapeutic strategy for TSC-associated epilepsy

Innovation Workshop: Newborn Screening Assay Development Awards

Michael Gelb, PhD
University of Washington
Proteomic assay for newborn screening of tuberous sclerosis complex

Carmen Priolo, MD, PhD
Brigham and Women’s Hospital
Application of glycomics to identify early biomarkers of TSC

TSC Biosample Seed Grant Awards

Joseph Bateman, BSc, PhD
King’s College London
Identification of novel mTOR targets in the TSC brain

Mark Keezer, MDCM, PhD
Centre Hospitalier de l’Université de Montréal
Biomarkers for epilepsy and renal angiomyolipomas among people with TSC

Hywel Williams, BSc, PhD
Cardiff University
Using Spatial-Transcriptomics to define gene expression profile of SEGAs in tuberous sclerosis complex 

TSC-DSC Clinical Fellowship

Felix Chan, PhD
Brown University
Lysine metabolism in tuberous sclerosis complex

FY 2020

Postdoctoral Fellowship Award

Katarzyna Klonowska, PhD
Brigham and Women’s Hospital
Polyclonal somatic mutations drive TSC tumorigenesis

Keith Hall Memorial Research Grant Award

Oded Volovelsky, MD, PhD
Hadassah Medical Center, Israel
Targeting the Endocannabinoid System in TSC-induced kidney disease

Past Grant Awards

FY 2020

Postdoctoral Fellowship Award

Bipan Deb, PhD
University of California, Berkeley
Investigating the origins of tubers using human cortical organoids

Research Grant Award

Robert Carson, MD, PhD
Vanderbilt University
Therapeutic benefits of nonsense suppression in TSC

TSC Biosample Repository Seed Grant

John J. Bissler, MD
University of Tennessee Health Sciences Center
Role of extracellular vesicles in TSC

Elaine Dunlop, BSc, PhD
Cardiff University
Investigating EV-associated RNA as a biomarker in tuberous sclerosis complex

Krinio Giannikou, PhD
Brigham and Women’s Hospital
A multi-omics platform to identify novel non-invasive diagnostic and prognostic biomarkers in TSC patients

FY 2019

Postdoctoral Fellowship Award

Ilaria Barone, PhD
Children’s Hospital, Boston
Harnessing the circadian clock to modulate TSC-related neuronal phenotypes

Elodie Villa, PhD
Northwestern University
Defining the molecular epigenetic signature downstream of mTORC1 signaling

Research Grant Award

Mustafa Sahin, MD, PhD
Children’s Hospital, Boston
Non-cell autonomous mechanisms of epilepsy in TSC2

Clinical Research Network Grant Award

Darcy A. Krueger, MD, PhD
Cincinnati Children’s Hospital Medical Center
Stopping TSC Onset and Progression 2 (STOP-2): Epilepsy prevention in TSC infants

Mustafa Sahin, MD, PhD
Children’s Hospital, Boston
Rare Diseases Clinical Research Consortium

TSC Biosample Repository Seed Grant

Carmen Priolo, MD, PhD
Brigham and Women’s Hospital, Inc.
Identification of immunogenic structures of the TSC glycome through glycan microarrays

Paul Dutchak, PhD
Université Laval
Novel approaches to treat TSC

FY 2018

Postdoctoral Fellowship Award

Christine Ochoa Escamilla, PhD
University of Texas Southwestern Medical Center
Neural Circuits Underlying Autism-Related Behaviors in Tuberous Sclerosis
Keith Hall Research Grant Award

Research Grant Award

Angélique Bordey, PhD
Yale University
Non-Cell Autonomous Effects in TSC Brain Malformations

Alan Dombkowski, PhD
Wayne State University
The Role of Exosomes in Epilepsy of TSC

TSC Biosample Repository Seed Grant

Laura S. Farach, MD
The University of Texas Health Science Center at Houston
Developing a Genetic Risk Prediction Model for Epilepsy in Patients with TSC

Hilaire C. Lam, PhD
Brigham and Women’s Hospital
Mitochondrial DNA Heteroplasmy in the Pathogenesis and Therapy of TSC

C. Joana Marques, PhD
University of Porto – Faculty of Medicine
Epigenetic and Transcriptional Analysis of TSC2 in Leukocyte DNA from Tuberous Sclerosis Patients

Jane J. Yu, PhD
University of Cincinnati
Quantification of Plasma Levels of Sphingolipids and Ceramides in Patients with TSC

FY 2017

Research Grant Award

Michael Evans, PhD
University of California, San Francisco
Developing New Ablative Therapies to Treat Tuberous Sclerosis Complex

Mark Thomas, PhD and Rosemary Ekong, PhD
University College London
The TSC1 and TSC2 Variation Database

Postdoctoral Fellowship Award

Peter Davis, MD
Children’s Hospital Boston
Brain Network Biomarkers of Epilepsy Development in TSC

You Feng, PhD
Brigham and Women’s Hospital
Dysregulated Phosphatidylcholine Metabolism in TSC and LAM Pathogenesis and Therapy
Keith Hall Research Grant Award
Co-funded with The LAM Foundation

FY 2016

Research Grant Award

Peter Davis, MD
Children’s Hospital Boston
Brain Network Biomarkers of Epilepsy Development in TSC

Jonathan Lipton, MD, PhD
Children’s Hospital Boston
The Circadian Clock as a Capacitor for TSC-related Phenotypes

Mark Nellist, PhD
Erasmus Universitair Medisch Centrum Rotterdam
Functional characterization of TSC1 and TSC2 variants associated with TSC

Sue Povey, MD, MA
University College London, London, UK
The TSC1 and TSC2 variation database

Co-funded with the Tuberous Sclerosis Association (UK)

Carmen Priolo, MD, PhD
Brigham and Women’s Hospital
Targeting the Lysophosphatidic Acid Pathway in Tuberous Sclerosis Complex

Postdoctoral Fellowship Award

Heng-Jia Liu, PhD
Brigham and Women’s Hospital
T-Cell Dysfunction in TSC: Mechanisms and Targeted Therapy

Peter Tsai, MD, PhD
UT Southwestern Medical Center
Impact of Cerebellar – Medial Prefrontal Cortical Circuits

FY 2015

Postdoctoral Fellowship Award

Polina Kosillo, DPhil
Sponsor: Helen Bateup, PhD
University of California, Berkeley
The impact of Tsc1 deletion on dopamine neurons

Research Grant Award

Mustafa Sahin, MD, PhD
Boston Children’s Hospital
Sonic hedgehog and ciliary signaling in TSC

Andrew Tee, PhD
Cardiff University
Analysis of novel therapies and survival mechanisms in TSC2 deficient cells

Rothberg Courage Award

Brendan Manning, PhD
Harvard University School of Public Health
Repurposing Approved Inhibitors of Purine Synthesis for TSC Treatment

FY 2014

Postdoctoral Fellowship Award

Gerta Hoxhaj, PhD
Sponsor: Brendan Manning, PhD
Harvard University School of Public Health, Boston, MA 
Role of the TSC complex component TBC1D7 in cell migration and invasion

Gina Lee, PhD
Sponsor: John Blenis, PhD
Weill Cornell Medicine, New York, NY
mTORC1-mediated mRNA alternative splicing in tuberous sclerosis and LAM

Research Grant Award

Gabriella D’Arcangelo, PhD
Rutgers University, New Brunswick, NJ
Developing TSC patient-derived NPCs

Michael Higley, MD, PhD
Yale University, New Haven, CT
Analysis and treatment of altered cortical network dynamics in TSC

Sue Povey, MD, MA
University College London, London, UK
The TSC1 and TSC2 variation database

Co-funded with the Tuberous Sclerosis Association (UK)

Wei Shi, MD, PhD
Children’s Hospital, Los Angeles, CA 
Lung mesenchymal TSC2 deletion in TSC lung disease

TSC Clinical Research Consortium

Mustafa Sahin, MD, PhD
Boston Children’s Hospital, Boston, MA
Administrative Core Support for Developmental Synaptopathies Associated with TSC, PTEN and SHANK3 Mutations

Five initial consortium sites received seed funding from the TSC Alliance and two NIH grants for clinical studies to identify markers of risk for autism and infantile spasms in TSC. They are:

  • Boston Children’s Hospital
  • Cincinnati Children’s Hospital Medical Center
  • University of Alabama, Birmingham
  • University of California, Los Angeles
  • University of Texas, Houston

FY 2013

Research Grant Award

Rebecca Ihrie, PhD
Vanderbilt University, Nashville, TN
Dissecting the effects of stem cell patterning on subependymal tumors

David Kwiatkowski, MD, PhD
Brigham and Women’s Hospital, Boston, MA
EPISTOP: clinical and molecular biomarkers of epilepsy in TSC
Co-funded with the European Commission

Carmen Priolo, MD, PhD
Brigham and Women’s Hospital, Boston, MA
Aberrant lipid metabolism in TSC diagnostics and therapeutics

FY 2012

Postdoctoral Fellowship Award

Jing Jeannie Li, PhD
Sponsor: John Blenis, PhD
Harvard Medical School, Boston, MA
Identification and development of metabolism inhibitors as a therapeutic strategy for tuberous sclerosis complex

Research Grant Award

Sue Povey, MD, MA
University College London, London, UK
The TSC1 and TSC2 variation database

TSC Alliance Rothberg Courage Award in Research

Mustafa Sahin, MD, PhD
Boston Children’s Hospital, Boston, MA
TSC Neurocognitive Clinical Trial Recruitment Acceleration Award

Darcy Krueger, MD, PhD
Cincinnati Children’s Hospital and Medical Center, Cincinnati, OH
TSC Neurocognitive Clinical Trial Recruitment Acceleration Award

TSC Clinical Research Consortium

Five initial consortium sites received seed funding from the TSC Alliance and two NIH grants for clinical studies to identify markers of risk for autism and infantile spasms in TSC

  • Boston Children’s Hospital
  • Cincinnati Children’s Hospital Medical Center
  • University of Alabama, Birmingham

FY 2011

Postdoctoral Fellowship Award

Brian Siroky, PhD
Sponsor: John Bissler, MD
Cincinnati Children’s Hospital Medical Center, Cincinnati, OH
Endoplasmic Reticulum Stress in the Pathogenesis and Treatment of TSC Renal Cystic Disease

Magdalena Tyburczy, PhD
Sponsor: David Kwiatkowski, MD, PhD
Brigham and Women’s Hospital, Boston, MA
Determining the Molecular Pathogenesis of TSC in No Mutation Identified (NMI) Patients

TSC Drug Screening Program

Seok-Hyung Kim, PhD
Vanderbilt University Medical Center, Nashville, TN
High-throughput Chemical Screening for compounds reversing TSC phenotypes in vivo using tsc2 mutant zebrafish

Mustafa Sahin, MD, PhD
Children’s Hospital Boston, Boston, MA
High Throughput Screening of Chemical Libraries in Primary Neurons

TSC Alliance Rothberg Courage Award in Research

Elizabeth Henske, MD
Brigham and Women’s Hospital, Boston, MA
Targeting Autophagy and Cellular Metabolism for the Treatment of TSC

John Bissler, MD
Cincinnati Children’s Hospital and Medical Center, Cincinnati, OH
MRI-Guided High Intensity Focused Ultrasound for TSC-Associated Renal and Pulmonary Disease

Hope Northrup, MD
University of Texas Health Science Center at Houston, Houston, TX
Identifying Additional Gene(s) That Cause Tuberous Sclerosis Complex by Whole Genome Sequencing

FY 2010

Postdoctoral Fellowship Award

Samira Bahl, PhD
Sponsor:  Vijaya Ramesh, PhD
Massachusetts General Hospital, Boston, MA
Elucidating the Role of Structural Variations in Autism Associated with Tuberous Sclerosis Complex

Alessia Di Nardo, PhD
Sponsor:  Mustafa Sahin, MD, PhD
Children’s Hospital, Harvard Medical School, Boston, MA
Regulation of Autophagy in Tuberous Sclerosis Complex

Cary Fu, MD
Sponsor:  Kevin Ess, MD, PhD
Vanderbilt University, Nashville, TN
The Role of the Tsc1 Gene in Interneuron Differentiation and Migration

TSC Drug Screening Program

Aristotelis Astrinidis, PhD
Drexel University College of Medicine, Philadelphia, PA
Screen of FDA-Approved Drugs as a Therapeutic Approach for Tuberous Sclerosis Complex 

John Frangioni, MD, PhD
Beth Israel Deaconess Medical Center, Boston, MA
Quantitation of In Vivo Response in TSC Tumors: A National Resource of the TSC Alliance

TSC Alliance Rothberg Courage Award in Research

Mustafa Sahin, MD, PhD
Children’s Hospital, Harvard Medical School, Boston, MA
TSC Neurocognitive Clinical Trial

Robert and Lisa Moss

Seizure Tracker, LLC, Alexandria, VA
Development and Implementation of an Epilepsy Clinical Trial Tool

FY 2009

Postdoctoral Fellowship Award

June Goto, PhD
Sponsor: David Kwiatkowski, MD, PhD
Brigham and Women’s Hospital, Harvard Medical School, Boston, MA
Generation and Characterization of Genetic Models for Cortical Tubers

Johnathan Lipton, MD, PhD
Sponsor: Mustafa Sahin, MD, PhD
Children’s Hospital, Boston, and Harvard Medical School, Boston, MA
Toward the Molecular Basis for Sleep Disorders in Tuberous Sclerosis Complex: The Circadian Link

Jean-Claude Platel, PhD
Sponsor: Angelique Bordey, PhD
Yale University School of Medicine, New Haven, CT
Contributions of Neonatal Neural Progenitors to TSC Lesions

Wei Qin, PhD
Sponsor: David Kwiatkowski, MD, PhD
Brigham and Women’s Hospital, Harvard School of Medicine, Boston, MA
High Throughput Sequencing for Mutation Identification in TSC Genes

Yonghao Yu, PhD
Sponsor: John Blenis, PhD
Harvard Medical School, Boston, MA
Characterization of the mTOR Signaling Pathways Using Quantitative Mass Spectrometry

TSC Innovator Award

Guy McKhann, II, MD
Columbia University Medical Center, New York City, NY
Aberrant Astrocytic Control of Neuronal Excitability in Tuberous Sclerosis: A Potential Therapeutic Target in TSC Epileptic Syndrome

Howard Weiner, MD
New York University Medical Center, New York, NY
Defining the Epileptogenic Zone in Tuberous Sclerosis Complex: Microelectrode Recordings in Children with Intractable Epilepsy and TSC

Raymond Yeung, MD
University of Washington, Seattle, WA
Glucose Restriction in TSC

TSC Alliance Rothberg Courage Award in Research

Frank McCormack, MD & Bruce Trapnell, MD
University of Cincinnati, Cincinnati, OH
MILES Trial

TSC Alliance Conference Grant

Petrus de Vries, MBChB, MRCPsych, PhD
Cambridge University & Society for the Study of Behavioural Phenotypes (SSBP), Cambridge, UK
Listening to Genetic Disorders: The Etiology and Treatment of Neurodevelopmental Disorders

TSC Alliance Supplemental Funding Award

Sandra Dabora, MD, PhD
Brigham & Women’s Hospital, Boston, MA
Supplement for TSC Preclinical Studies and Clinical Trials

FY 2008

Postdoctoral Fellowship Award

Linda DiBella, PhD
Sponsor: Zhaoxia Sun, PhD
Yale University, New Haven, CT
Investigating a Link Between the Cilium and the TSC/mTOR Pathway

Cheryl Doughty, PhD
Sponsor:  David Kwiatkowski, MD, PhD
Brigham & Women’s Hospital, Boston, MA
Investigation of TSC2 Missense Mutations

Junior Investigator Award

Kevin Ess, MD, PhD
Vanderbilt University, Nashville, TN
Role of the Tuberin GAP Domain in Neural Progenitor Cells

Shao-Jun Tang, PhD
University of California, Irvine, CA
Roles of TSC2 in Regulation of Dendritic Protein Synthesis and Synaptic Plasticity

Senior Investigator Award

Michael Wong, MD, PhD
Washington University, St. Louis, MO
Rational Therapy for Neurological Manifestations in a Mouse Model of TSC

TSC Alliance Rothberg Courage Award in Research

Frank McCormack, MD & Bruce Trapnell, MD
University of Cincinnati, Cincinnati, OH
MILES Trial

Other Funding

NIH Grant Award, Co-Funded by the National Cancer Institute, National Institutes of Health and the TSC Alliance

Arnold Kristof, MDCM
McGill University, Montreal, Quebec, Canada
mTOR-containing Protein Complexes in the Pathogenesis of Tuberous Sclerosis

PKD/TSC Research Award co-funded by the TSC Alliance and the PKD Foundation

Elizabeth Petri Henske, MD
Fox Chase Cancer Center, Philadelphia, PA
Roles of Tuberin (TSC2) and Rheb in Cystic Kidney Disease

Cheryl Walker, PhD

M.D. Anderson Cancer Center, University of Texas, Smithville, TX
C-SRC Regulation of the Functional PKD-1 TSC2 Interaction

FY 2007

TSC Alliance Rothberg Courage Award in Research

Frank McCormack, MD & Bruce Trapnell, MD
University of Cincinnati, Cincinnati, OH
MILES Trial  

FY 2002 – 2005

TSC Alliance Rothberg Courage Award in Research

John Blenis, PhD
Lewis Cantley, PhD
Iswar Hariharan, MBBS, PhD
David Kwiatkowski, MD, PhD
Timothy Mitchison, PhD

Harvard Medical School and Brigham & Women’s Hospital, Boston, MA
Role of the TSC1/2 Complex in Regulation of the mTOR Pathway

David Austin, PhD
Yale University, New Haven, CT
Screening of Potential Therapeutics for TSC

Tian Xu, PhD
Yale University, New Haven, CT
Role of the TSC/Insulin Signaling Pathway in the Pathogenesis of TSC

Elizabeth Petri Henske, MD
Fox Chase Cancer Center, Philadelphia, PA
Effects of Estrogen and Progesterone on Angiomyolipoma Growth and Migration

 

Other TSC Funding Opportunities

Additional funding opportunities for TSC research may be available through the federal agencies and non-federal organizations listed below.  The TSC Alliance also looks to collaborate with other organizations that have shared research priorities and are interested in partnering or co-funding opportunities.

If you would like to add your organization to the list below or are interested in the possibility of exploring co-funding opportunities, please contact Steve Roberds.

For Inquiries, Contact:

Zoë Fuchs
Manager, Translational Research
301-562-9890