There is limited literature on eating-related difficulties and disorders in tuberous sclerosis complex (TSC), but difficulties with eating do present in individuals with TSC. Eating difficulties may be similar to those seen in typically developing children (e.g., picky eating), be associated with TAND-related manifestations (e.g., autism-related restricted eating, or mood and anxiety-related over/under-eating) or be associated with physical health in TSC (e.g., mouth ulcers or other adverse effects of medications, physical ill health, pain).
Sleep difficulties are common in children and adults in the general population but are more pronounced in TSC. Sleep difficulties may be a “cause” of some TAND and other neurological manifestations (e.g., leading to dysregulated or overactive and impulsive behaviors, poor scholastic performance, or seizures) or a “consequence” (e.g., autism-related rigid sleep routines, mood and anxiety-related insomnia, waking due to nocturnal seizures, or adverse effects of medications).
Identifying the root cause of eating and/or sleep manifestations is a priority first step.
The consensus panel recommends the following: