Dean Aguiar, PhD • daguiar@tscalliance.org
Vice President, Translational Research
Zoë Fuchs • zfuchs@tscalliance.org
Senior Manager, Translational Research
TSC Alliance Preclinical Consortium
American Epilepsy Society • Poster in Collaboration with PsychoGenics, Inc.
Poster Session 1 • Saturday, December 6, 2025, 12:00-5:00 pm
Poster #1.203 • “mTOR Inhibitors Decrease Seizures and Enhance Survival in a Mouse Model of Tuberous Sclerosis Complex (TSC)”
Please stop by our booth #639 to connect with our team and learn more about us!
PSTR320.20 | 8857
Title: Dose-response of mTOR inhibitors in a nonclinical model of tuberous sclerosis complex (TSC) associated epilepsy – Conducted by the TSC Preclinical Consortium (See pg. 149)
TSC Animal Models (epilepsy and/or behavioral)
- Tsc1 & Tsc2 stochastic models
Selected Publications:
The role of the TSC Alliance in advancing therapy development: a patient organization perspective
Inhibition of MEK-ERK Signaling Reduces Seizures in Two Mouse Models of Tuberous Sclerosis Complex