Neuropsychological cluster recommendations

• Everyone with TSC should receive a comprehensive assessment of their intellectual ability at the time of diagnosis to identify their profile of strengths and weaknesses.
• Children and adults with TSC should have ongoing (at least annual) screening and monitoring for the presence or emergence of neuropsychological difficulties.
• Neuropsychological deficits can have a major impact on functional ability and may present in various ways, such as anxiety and feeling overwhelmed, dysregulated behaviours, difficulties in education, or struggles in work.
• Individuals with known neurodevelopmental disorders (e.g., ADHD, autism, learning disorders) should receive a formal neuropsychological evaluation to understand their profile of strengths and weaknesses, not just be screened for such deficits.
• Non-pharmacological coaching and training strategies should be used to strengthen areas of neuropsychological deficits, for example, executive coaching for working memory, cognitive flexibility or planning deficits.
• Neuropsychological deficits may require specific accommodations or supports in education and/or the workplace.