Overactive/Impulsive cluster recommendations

• Overactive and impulsive behaviors are common in TSC and should be monitored in all individuals to ensure early detection and treatment
• All individuals with overactive and impulsive behaviors should be considered for a clinical diagnostic assessment for ADHD.
• ADHD in TSC should be treated using the same evidence-based approaches and interventions for the general population, including behavioral supports and pharmacological interventions.
• When someone has moderate to severe ADHD, treatment with methylphenidate or other stimulant medications should be considered.
• Even when ADHD is accompanied with epilepsy, intellectual disability, autism, or other physical or TAND manifestations, ADHD symptoms may respond appropriately to treatment.
• Further research is required to improve the understanding of overactivity, restlessness, and impulsivity in TSC.