One of the most common neurological features of tuberous sclerosis complex (TSC) are seizures. This feature occurs in 84% of individuals with TSC.

In some cases, seizures can start as early as infancy with the diagnosis of infantile spasms. In other cases, seizures may develop in adolescents or adulthood which could include focal onset and generalized seizures. There are various types of seizures which can occur, and it is important that seizures are treated and monitored. Standards of care, including medications, to treat seizures are not successful for every individual. There are up to two – thirds of individuals with TSC who will have, intractable epilepsy, meaning their seizures do not respond favorably to standard antiseizure medications.

Learn more about epilepsy in TSC:

Reviewed by Ashley Pounders, MSN, FNP-C, Director of Medical Affairs, TSC Alliance, November 2023.

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