TSC Alert

Archive for April, 2018

Call for Proposals: TSC2+/- A/J mice – Due May 4

The TSC Preclinical Consortium is currently running three animal models, one of which is the Tsc2+/- A/J strain (Woodrum et al 2010, Guo and Kwiatkowski 2013). A/J mice are challenging to breed, but the Preclinical Consortium’s colony at the Van Andel Research Institute is now in very good shape. Large cohorts of age-matched mice are bred for testing candidate drugs using standardized protocols at a contract research organization. However, as a by-product of growing the colony, we have smaller numbers of non-age-matched mice, which could provide valuable data for other research questions. We currently have available 31 female Tsc2+/- A/J…