Are you looking for samples from TSC patients to use in your lab? The TSC Biosample Repository has a growing collection of samples tied to phenotypic data. In most cases, we can ship these samples at no charge to the investigator.
To date, we have shipped 1,717 samples for use in diverse projects, ranging from quantification of sphingolipids in plasma to investigating mitochondrial DNA heteroplasmy.
As of May 1, 2022, the TSC Biosample Repository has the following in their inventory:
Whole Blood
- 106 DNA*
- 1 PBMC
- 605 Plasma
- 627 WBC – Buffy Coat
- 1 Whole Blood (cord blood)
Buccal
- 266 Buccal Cells
- 101 DNA*
- 1 Embedded Block (buccal mucosa)
- 1 Glass H&E Slide (buccal mucosa)
Tissue
Please see full inventory, including tissue specimens here.
*Please note that we are able to extract DNA from additional whole blood or buccal samples as needed.
We highly recommend you contact the TSC Alliance at biosample@tscalliance.org to discuss available samples.
Because biosamples are linked to data in the Natural History Database, applicants may request subsets of biosamples based on clinical phenotypes, age, sex, etc., to compare, for example, samples from individuals with TSC who developed angiomyolipomas at different ages or not at all. Additional data from the Natural History Database relevant to the project may be requested for each sample, as well.
In addition to patient samples, we also have a license to distribute the TSC1- and TSC2-knockout HEK293T cell lines from the Nellist laboratory at Erasmus MC to researchers in the Americas.
If you would like to request biosamples, please follow the instructions on our Biosample Repository page.